微囊化技术研究进展及其在农药领域的应用

李北兴; 张大侠; 张灿光; 管磊; 王凯; 刘峰

doi:10.3969/j.issn.1008-7303.2014.05.01

微囊化技术研究进展及其在农药领域的应用

doi: 10.3969/j.issn.1008-7303.2014.05.01

李北兴¹,
张大侠^1,2,
张灿光¹,
管磊¹,
王凯¹,
刘峰^1,

1.
山东农业大学植物保护学院/农药毒理与应用技术重点实验室, 山东泰安 271018
2.
山东农业大学农药环境毒理研究中心, 山东泰安 271018

基金项目:

公益性行业（农业）科研专项经费项目（201303027）

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出版历程
- 收稿日期: 2014-01-17
- 修回日期: 2014-05-21
- 刊出日期: 2014-10-16

Research advances and application prospects of microencapsulation techniques in pesticide

1.
Key Laboratory of Pesticide Toxicology & Application Technique, Department of Plant Protection, Shandong Agricultural University, Tai'an 271018, Shandong Province, China
2.
Research Center of Pesticide Environmental Toxicology, Shandong Agricultural University, Tai'an 271018, Shandong Province, China

摘要

摘要: 综述了近年来常用的微囊化技术（喷雾干燥法、溶剂蒸发法、界面聚合法、原位聚合法、相分离法和自组装法）的研究进展及应用现状，并介绍了微流体及配位法两种微囊化新技术。结合国内农药微囊制剂的登记情况，提出应依据微囊化的目的开发相应的农药微囊产品，如掩蔽气味、抗光解、减少淋溶和飘移等，并应结合药剂的理化特性、防治对象、用药环境、施药方式、实践需要和最终的防治效果等综合因素，决定该农药是否适宜开发成微囊产品，并选择适宜的壁材、微囊化技术及剂型。指出种子处理剂微囊、果蔬保鲜剂微囊、植物精油微囊、昆虫性信息素微囊及土壤处理剂微囊是目前亟待拓展的微囊化研究方向，此外，芯材在不同环境中的释放动态、因缓释导致的农药残留问题及壁材的降解等也值得研究者关注。总之，研究开发安全、可降解的囊壁材料，探索高工效和真正具有控释效果的微囊化技术具有重要意义。
- 微囊化 /
- 微流体技术 /
- 配位聚合物 /
- 囊壁材料 /
- 控制释放
Abstract: Research advances and application prospects of common microencapsulation techniques including spray drying, solvent evaporation, interfacial polymerization, in situ polymerization, phase separation and self-assembly were summarized, and novel microencapsulation methods such as microfluidic technique and coordination method were introduced. Current situation of microcapsule registration in China was analyzed, and it was proposed that the development of microcapsule products should take the objective of microencapsulation into consideration, such as masking odors, anti-photolysis, reducing leaching and drift of active ingredients. Meanwhile, the physical and chemical characteristics of pesticides, the control targets, the application environment and methods, the practical requirements and the ultimate control efficacy were all factors that should be assessed to determine whether the pesticides suitable for microencapsulation or not, and appropriate wall materials, microencapsulation methods and formulations should be selected. Further study on microencapsulation is needed, especially on microcapsule for seed treatment or soil treatment, microcapsule embedding fresh-keeping agent, essential oil or sex pheromone. In addition, more attention should be paid to the release dynamics of core material in different environment, pesticide residues due to slow release, degradation of wall materials and so on. It is very important to develop highly safe and biodegradable wall materials and explore microencapsulation techniques with high-efficacy and practical release-control capacity.
- microencapsulation /
- microfluidic technique /
- coordination complex /
- wall material /
- controlled release

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参考文献(98)

XU Jin, ZHAO Wenxiu, NING Yawei, et al. Improved stability and controlled release of _ω3/ _ω6 polyunsaturated fatty acids by spring dextrin encapsulation[J]. Carbohydr Polym, 2013, 92(2): 1633-1640.

WANG Guoying, CHEN Juan, SHI Yanping. Preparation of microencapsulated xanthophyll for improving solubility and stability by nanoencapsulation[J]. J Food Eng, 2013, 117(1): 82-88.

AGHBASHLO M, MOBLI H, RAFIEE S, et al. Optimization of emulsification procedure for mutual maximizing the encapsulation and exergy efficiencies of fish oil microencapsulation[J]. Powder Technol, 2012, 225: 107-117.

AGHBASHLO M, MOBLI H, RAFIEE S, et al. Energy and exergy analyses of the spray drying process of fish oil microencapsulation[J]. Biosyst Eng, 2012, 111(2): 229-241.

SCHER H B, RODSON M, LEE K S. Microencapsulation of pesticides by interfacial polymerization utilizing isocyanate or aminoplast chemistry[J]. Pestic Sci, 1998, 54(4): 394-400.

FRIEDMAN-RUDOVSKY J. With novel paint, chemist aims to vanquish the Vinchuca[J]. Science, 2012, 336(6082): 666-667.

STOJAKOVC D, BUGARSKI B, RAJIC N. A kinetic study of the release of vanillin encapsulated in Carnauba wax microcapsules[J]. J Food Eng, 2012, 109(3): 640-642.

WANG Qiuxia, YAN Dongdong, MAO Liangang, et al. Efficacy of 1, 3-dichloropropene plus chloropicrin gelatin capsule formulation for the control of soilborne pests[J]. Crop Prot, 2013, 48: 24-28.

XIE Zhiyi, CHEN Nengchang, LIU Chengshuai, et al. Synthesis and characterization of ethylenediamine tetraacetic acid tetrasodium salt loaded in microcapsules with slow release properties[J]. Chin J Chem Eng, 2010, 18(1): 149-155.

ZHANG Ting, ZHANG Min, TONG Xiaomei, et al. Optimal preparation and characterization of poly(urea-formaldehyde) microcapsules[J]. J Appl Polym Sci, 2010, 115(4): 2162-2169.

YEH K W, CHANG C P, YAMAMOTO T, et al. Release behavior of capsules loaded by volatile liquid in multicores[J]. Colloid Polyme Sci, 2012, 290(15): 1583-1591.

MA Ying, ZHANG Ying, WANG Yu, et al. Study of the effect of membrane thickness on microcapsule strength, permeability, and cell proliferation[J]. J Biomed Mater Res, Part A, 2013, 101A(4): 1007-1015.

ZHANG Maojie, WANG Wei, XIE Rui, et al. Microfluidic fabrication of monodisperse microcapsules for glucose-response at physiological temperature[J]. Soft Matter, 2013, 9(16): 4150-4159.

COMISKEY B, ALBERT J D, YOSHIZAWA H, et al. An electrophoretic ink for all-printed reflective electronic displays[J]. Nature, 1998, 394(6690): 253-255.

SUTTER S C, BUERA M P, ELIZALDE B E. β-Carotene encapsulation in a mannitol matrix as affected by divalent cations and phosphate anion[J]. Int J Pharm, 2007, 332(1–2): 45-54.

郑立辉. 尿素包合法制取低熔点石蜡的研究[J]. 精细石油化工, 2002(6): 11-13. ZHENG Lihui. Preparation of low melting point paraffin by urea-adduct method[J]. Spec Petrochem, 2002(6): 11-13.(in Chinese)

林书乐, 王坤, 程江, 等. 微胶囊技术新进展[J]. 高分子材料科学与工程, 2012, 28(5): 179-182. LIN Shule, WANG Kun, CHENG Jiang, et al. Recent progress in microencapsulation technology[J]. Polym Mater Sci Eng, 2012, 28(5): 179-182.(in Chinese)

张武杰, 李保国, 张超, 等. 静电喷雾法制备海藻酸钙-羧甲基纤维素钠液芯微胶囊的工艺选优[J]. 上海理工大学学报, 2007, 29(4): 349-352. ZHANG Wujie, LI Baoguo, ZHANG Chao, et al. Optimizing lecnological parameters for preparing calcium alginate-sodium carboxymethyl cellulose liquid core microcapsules by using electrostatic spray method[J]. J Univ Shanghai Sci Technol, 2007, 29(4): 349-352.(in Chinese)

O'DONNELL P B, MC-GINITY J W. Preparation of microspheres by the solvent evaporation technique[J]. Adv Drug Delivery Rev, 1997, 28(1): 25-42.

李志强, 任彦荣. 微胶囊技术及其应用研究进展[J]. 化学推进剂与高分子材料, 2004, 2(6): 19-23. LI Zhiqiang, REN Yanrong. Microencapsulation technology and research progress of its application[J]. Chem Propellants Polym Mater, 2004, 2(6): 19-23.(in Chinese)

NIXON J R. Preparation of microcapsules with possible pharmaceutical use[J]. Endeavour, 1985, 9(3): 123-128.

SOPPIMATH K S, KULKARNI A R, AMINABHAVI T M, et al. Cellulose acetate microspheres prepared by O/W emulsification and solventevaporation method[J]. J Microencapsulation, 2001, 18(6): 811-817.

付颖, 叶非, 王常波. 微胶囊剂农药发展概述[J]. 农药科学与管理, 2001, 22(4): 39-41. FU Ying, YE Fei, WANG Changbo. The development of microencapsulation of pesticide[J]. Pestic Sci Admin, 2001, 22(4): 39-41.(in Chinese)

ZHANG Jing, COULSTON R J, JONES S T, et al. One-step fabrication of supramolecular microcapsules from microfluidic droplets[J]. Science, 2012, 335(6069): 690-694.

EJIMA H, RICHARDSON J J, LIANG K, et al. One-step assembly of coordination complexes for versatile film and particle engineering[J]. Science, 2013, 341(6142): 154-157.

TORRES P, VILLA F, GONZÁLEZ J, et al. Preparation and characterization of the emamectin benzoate/hydroxypropyl-b-cyclodextrin inclusion complex[J]. J Chil Chem Soc, 2011, 56(4): 951-954.

张可达, 徐冬梅, 王平. 微胶囊化方法[J]. 功能高分子学报, 2001, 14(4): 474-480. ZHANG Keda, XU Dongmei, WANG Ping. Microencapsulation method[J]. J Funct Polym, 2001, 14(4): 474-480. (in Chinese)

吕静, 李丹, 孙建兵, 等. 低分子量聚乳酸包膜尿素的缓释特性及其减少氨挥发的作用[J]. 中国农业科学, 2012, 45(2): 283-291. LÜ Jing, LI Dan, SUN Jianbing, et al. Slow release characteristics of the low molecular weight polylactic acid-coated urea and its reduction effects on soil ammonia volatilization[J]. Scientia Agricultura Sinica, 2012, 45(2): 283-291. (in Chinese)

夏晓静, 周建平, 王翔, 等. 伊维菌素聚乳酸微球的制备[J]. 中国药科大学学报, 2004, 35(5): 429-432. XIA Xiaojing, ZHOU Jianping, WANG Xiang, et al. Preparation of polylactic acid microspheres loading ivermectin[J]. J China Pharm Univ, 2004, 35(5): 429-432. (in Chinese)

郭瑞峰, 黄彬彬, 杨晓伟, 等. 毒死蜱-聚乳酸微球的制备及其性能评价[J]. 农药学学报, 2011, 13(4): 409-414. GUO Ruifeng, HUANG Binbin, YANG Xiaowei, et al. Preparation and characteristics analysis of microspheres of chlorpyrifos and polylactic acid[J]. Chin J Pestic Sci, 2011, 13(4): 409-414. (in Chinese)

CARRERAS N, ACUÑA V, MARTÍ M, et al. Drug release system of ibuprofen in PCL-microspheres[J]. Colloid Polym Sci, 2013, 291(1): 157-165.

杨石有, 刘德坤, 张翠, 等. 毒死蜱微球和乳油在水中的消解动态及其对白纹伊蚊幼虫的毒力[J]. 农药学学报, 2013, 15(4): 464-468. YANG Shiyou, LIU Dekun, ZHANG Cui, et al. Decline dynamics of chlorpyrifos microspheres and emulsifiable concentrate in water and its toxicity to the larvae of Aedes albopictus[J]. Chin J Pestic Sci, 2013, 15(4): 464-468. (in Chinese)

孟锐, 刘双清, 朱锐, 等. 可降解聚碳酸亚丙酯-毒死蜱微胶囊的制备及缓释性能评价[J]. 农药学学报, 2012, 14(5): 565-573. MENG Rui, LIU Shuangqing, ZHU Rui, et al. Preparation of degradable poly(propylene carbonate)-chlorpyrifos microcapsule and performance evaluation on its controlled release[J]. Chin J Pestic Sci, 2012, 14(5): 565-573. (in Chinese)

MATSUNAMI Y, ICHIKAWA K. Characterization of the structures of poly(urea-urethane) microcapsules[J]. Int J Pharm, 2002, 242(1-2): 147-153.

SOTO-PORTAS M L, ARGILLIER J F, MECHIN F, et al. Preparation of oily core polyamide microcapsules via interfacial polycondensation[J]. Polym Int, 2003, 52(4): 522-527.

李北兴, 王凯, 张大侠, 等. 高含量二甲戊灵微囊悬浮剂物理稳定性的影响因素及优化[J]. 农药学学报, 2013, 15(6): 692-698. LI Beixing, WANG Kai, ZHANG Daxia, et al. Factors that affecting physical stability of high content pendimethalin capsule suspension and its optimization[J]. Chin J Pestic Sci, 2013, 15(6): 692-698. (in Chinese)

傅桂华, 钟滨, 陈建宇, 等. 界面聚合法制备农药微胶囊剂的研究[J]. 农药, 2005, 44(2): 66-68. FU Guihua, ZHONG Bin, CHEN Jianyu, et al. Pesticide microcapsules prepared by an interfacial polymerization method[J]. Chin J Pestic, 2005, 44(2): 66-68. (in Chinese)

陶晡, 康占海, 张金林. 硅酸镁铝及其与黄原胶协同使用对30% 辛硫磷微囊悬浮剂贮存物理稳定性的影响[J]. 农药学学报, 2012, 14(5): 574-578. TAO Bu, KANG Zhanhai, ZHANG Jinlin. Study on influence of veegum and the coordination of veegum with xanthan gum to physical stability of phoxim 300 capsule suspension[J]. Chin J Pestic Sci, 2012, 14(5): 574-578. (in Chinese)

HICKEY J, BURKE N A D, STÖVER H D H. Layer-by-layer deposition of clay and a polycation to control diffusive release from polyurea microcapsules[J]. J Membr Sci, 2011, 369(1-2): 68-76.

HONG K J, PARK S M. Preparation and characterization of polyurea microcapsules with different diamines[J]. Mater Res Bull, 1999, 34(6): 963-969.

TAKASU M, KAWAGUCHI H. Preparation of colored latex with polyurea shell by miniemulsion polymerization[J]. Colloid Polym Sci, 2005, 283(7): 805-811.

GAUDIN F, SINTES-ZYDOWICZ N. Poly(urethane-urea) nanocapsules prepared by interfacial step polymerisation in miniemulsion: the droplet size: a key-factor for the molecular and thermal characteristics of the polymeric membrane of the nanocapsules?[J]. Colloids Surf A, 2011, 384(1-3): 698-712.

ZHU Aiping, LI Fengjuan, JI Lijun. Poly(lactic acid)/N-maleoylchitosan core-shell capsules: preparation and drug release properties[J]. Colloids Surf B, 2012, 91: 162-167.

TSUDA N, OHTSUBO T, FUJI M. Preparation of self-bursting microcapsules by interfacial polymerization[J]. Adv Powder Technol, 2012, 23(6): 724-730.

JABBARI E, KHAKPOUR M. Morphology of and release behavior from porous polyurethane microspheres[J]. Biomaterials, 2000, 21(20): 2073-2079.

WANG Mian, ZHANG Kui, WU Wei, et al. Synthesis of temperature-responsive hybrid capsules and their controlled release property[J]. Colloids Surf A, 2011, 385(1-3): 126-133.

KIM K S, LEE J Y, PARK B J, et al. Synthesis and characteristics of microcapsules containing electrophoretic particle suspensions[J]. Colloid Polym Sci, 2006, 284(7): 813-816.

FAN Chuangjie, ZHOU Xiaodong. Influence of operating conditions on the surface morphology of microcapsules prepared by in situ polymerization[J]. Colloids Surf A, 2010, 363(1-3): 49-55.

常怀春, 吕通建, 郭轶超, 等. 酚醛树脂为囊壁的微胶囊红磷的制备及其在电缆料中的阻燃应用[J]. 塑料工业, 2011, 39(增刊1): 89-92. CHANG Huaichun, LÜ Tongjian, GUO Yichao, et al. Preparation of microencapsulated red phosphorus with phenol-formaldehyde resin as shell and its flame-retardant application in cable compound[J]. China Plast Ind, 2011, 39(Suppl.1): 89-92.(in Chinese)

KAGE H, KAWAHARA H, HAMADA N, et al. Operating conditions and microcapsules generated by in situ polymerization[J]. Adv Powder Technol, 2002, 13(3): 265-285.

赵德, 刘峰, 慕卫, 等. 毒死蜱微囊悬浮剂的制备及微囊化条件的优化[J]. 农药学学报, 2006, 8(1): 77-82. ZHAO De, LIU Feng, MU Wei, et al. Preparation of chlorpyrifos aqueous capsule suspension and optimization of encapsulation conditions[J]. Chin J Pestic Sci, 2006, 8(1): 77-82. (in Chinese)

SUKHORUKOV G B, ANTIPOV A A, VOIGT A, et al. pH-controlled macromolecule encapsulation in and release from polyelectrolyte multilayer nanocapsules[J]. Macromol Rapid Commun, 2001, 22(1): 44-46.

ATKKIN R, DAVIES P, HARDY J, et al. Preparation of aqueous core/polymer shell microcapsules by internal phase separation[J]. Macromolecules, 2004, 37(21): 7979-7985.

SU Junfeng, SCHLANGEN E. Synthesis and physicochemical properties of high compact microcapsules containing rejuvenator applied in asphalt[J]. Chem Eng J, 2012, 198-199: 289-300.

SU Junfeng, SCHLANGEN E, QIU Jian. Design and construction of microcapsules containing rejuvenator for asphalt[J]. Powder Technol, 2013, 235: 563-571.

SU Junfeng, WANG Xinyu, DONG Hua. Influence of temperature on the deformation behaviors of melamine-formaldehyde microcapsules containing phase change material[J]. Mater Lett, 2012, 84: 158-161.

黄彬彬, 骆桂红, 童小钰, 等. 复凝聚法制备甲氨基阿维菌素苯甲酸盐微囊[J]. 农药学学报, 2009, 11(4): 493-498. HUANG Binbin, LUO Guihong, TONG Xiaoyu, et al. Preparation of emamectin-benzoate microcapsules by complex coacervation[J]. Chin J Pestic Sci, 2009, 11(4): 493-498. (in Chinese)

NAKAGAWA K, NAGAO H. Microencapsulation of oil droplets using freezing-induced gelatin-acacia complex coacervation[J]. Colloids Surf A, 2012, 411: 129-139.

SHIMOKAWA K I, SAEGUSA K, WADA Y, et al. Physicochemical properties and controlled drug release of microcapsules prepared by simple coacervation[J]. Colloids Surf B, 2013, 104: 1-4.

关英, 张拥军, 张文静, 等. 层层自组装膜的研究: 从基础到生物医学领域中的应用[J]. 高分子通报, 2013(1): 40-52. GUAN Ying, ZHANG Yongjun, ZHANG Wenjing, et al. Layer-by-layer assembled films: from fundamentals to biomedical applications[J]. Polym Bull, 2013(1): 40-52. (in Chinese)

仝维鋆, 高长有. 层层组装微胶囊的制备及其智能响应与物质包埋释放性能[J]. 高等学校化学学报, 2008, 29(7): 1285-1298. TONG Weijun, GAO Changyou. Layer-by-layer assembled microcapsules: fabrication, stimuli-responsivity, loading and release[J]. Chem J Chin Univ, 2008, 29(7): 1285-1298. (in Chinese)

PONGJANYAKUL T, PUTTIPIPATKHACHORN S. Modulating drug release and matrix erosion of alginate matrix capsules by microenvironmental interaction with calcium ion[J]. Eur J Pharm Biopharm, 2007, 67(1): 187-195.

WICHCHUKIT S, OZTOP M H, MC-CARTHY M J, et al. Whey protein/alginate beads as carriers of a bioactive component[J]. Food Hydrocolloids, 2013, 33(1): 66-73.

SHULKIN A, STÖVER H D H. Microcapsules from styrene-maleic anhydride copolymers: study of morphology and release behavior[J]. J Membr Sci, 2002, 209(2): 433-444.

TENG Zi, LUO Yangchao, WANG Qin. Carboxymethyl chitosan-soy protein complex nanoparticles for the encapsulation and controlled release of vitamin D₃[J]. Food Chem, 2013, 141(1): 524-532.

HUI P C L, WANG Wenyi, KAN Chiwai, et al. Preparation and characterization of chitosan/sodium alginate (CSA) microcapsule containing cortex moutan[J]. Colloids Surf A, 2013, 434: 95-101.

DINSMORE A D, HSU M F, NIKOLAIDES M G, et al. Colloidosomes: selectively permeable capsules composed of colloidal particles[J]. Science, 2002, 298(5595): 1006-1009.

贾进伟, 张绍勇, 张爽, 等. 负载戊唑醇的壳聚糖纳米胶囊的制备与性能研究[J]. 农药学学报, 2013, 15(5): 582-586. JIA Jinwei, ZHANG Shaoyong, ZHANG Shuang, et al. Preparation and properties of chitosan nanocapsules loaded with tebuconazole[J]. Chin J Pestic Sci, 2013, 15(5): 582-586. (in Chinese)

周斌, 赵静. 层层自组装制备阿维菌素微胶囊及其释药行为[J]. 精细化工, 2008, 25(7): 625-627. ZHOU Bin, ZHAO Jing. Microencapsulation and release kinetics of abamectin by layer-by-layer polyelectrolyte self-assembly[J]. Fine Chem, 2008, 25(7): 625-627. (in Chinese)

LEE M H, HRIBAR K C, BRUGAROLAS T, et al. Harnessing interfacial phenomena to program the release properties of hollow microcapsules[J]. Adv Funct Mater, 2012, 22(1): 131-138.

BENTLEY W E, PAYNE G F. Natures other self-assemblers[J]. Science, 2013, 341(6142): 136-137.

MAL P, BREINER B, RISSANEN K, et al. White phosphorus is air-stable within a self-assembled tetrahedral capsule[J]. Science, 2009, 324(5935): 1697-1699.

中华人民共和国农业部农药检定所. 农药电子手册单机企业版[CP]. (2014-01). ICAMA of China. The e-pesticide manual (stand-alone edition) [CP]. (2014-01).

吴学民, 徐妍. 噻虫啉微囊粉剂和悬浮剂及其制备方法和用途: 中国，201010103001 [P]. 2010-06-23. WU Xuemin, XU Yan. Preparation method and uses of thiacloprid CJF and suspension concentrate: CN, 201010103001 [P]. 2010-06-23.

孙培章. 30% 毒死蜱微囊悬浮剂防治花生蛴螬田间药效试验[J]. 安徽农业科学, 2008, 36(27): 11839, 11863. SUN Peizhang. Field efficacy trials of 30% microcapsule suspension of chlorpyrifos against peanut white grub[J]. J Anhui Agri Sci, 2008, 36(27): 11839, 11863.(in Chinese)

陆年宏, 谭伟龙, 钱趋程, 等. JWX-Ⅲ型微胶囊悬浮剂滞留喷洒对蚊蝇的灭效研究[J]. 中华卫生杀虫药械, 2013, 19(2): 108-110. LU Nianhong, TAN Weilong, QIAN Qucheng, et al. Effect observation on JWX-Ⅲ in residual spraying against mosquitoes and flies[J]. Chin J Hyg Insect Equip Apr, 2013, 19(2): 108-110. (in Chinese)

马春娟, 陶丽华. 复凝聚法制备嘧菌酯微囊剂工艺研究[J]. 安徽农业科学, 2008, 36(9): 3496, 3508. MA Chunjuan, TAO Lihua. Study on the technology of preparing azoxystrobin microcapsules by complex coacervation[J]. J Anhui Agric, 2008, 36(9): 3496, 3508. (in Chinese)

周训卿, 曹立冬, 刘亚静, 等. 嘧菌酯微囊的制备及其性能表征[J]. 农药学学报, 2014, 16(2): 213-219. ZHOU Xunqing, CAO Lidong, LIU Yajing, et al. Preparation and performance characteristics of azoxystrobin microcapsules[J]. Chin J Pestic Sci, 2014, 16(2): 213-219. (in Chinese)

焦永康, 康占海, 庞民好, 等. 10%吡虫啉微胶囊悬浮剂的研制及其对棉蚜的防治效果[J]. 河北农业大学学报, 2011, 34(6): 83-86. JIAO Yongkang, KANG Zhanhai, PANG Minhao, et al. The preparation of 10% imidacloprid CS and the control efficacy on cotton aphids[J]. J Agric Univ Hebei, 2011, 34(6): 83-86. (in Chinese)

韩志任, 杜有辰, 李刚, 等. 阿维菌素脲醛树脂微胶囊的制备及其缓释性能[J]. 农药学学报, 2007, 9(4): 405-410. HAN Zhiren, DU Youchen, LI Gang, et al. Preparation and sustained-release behavior of abamectin urea-formaldehyde resin microcapsules[J]. Chin J Pestic Sci, 2007, 9(4): 405-410. (in Chinese)

KJÆR J, ERNSTSEN V, JACOBSEN O H, et al. Transport modes and pathways of the strongly sorbing pesticides glyphosate and pendimethalin through structured drained soils[J]. Chemosphere, 2011, 84(4): 471-479.

UTULU S N, AKOBUNDU I O, FAYEMI A A A. Persistence and downward movement of some selected herbicides in the humid and subhumid tropics[J]. Crop Prot, 1986, 5(2): 129-136.

葛艳蕊, 冯薇, 吕均超, 等. 除草剂广灭灵脲醛树脂微胶囊剂的研制[J]. 河北科技大学学报, 2010, 31(1): 48-51. GE Yanrui, FENG Wei, LÜ Junchao, et al. Study on preparation of urea-formaldehyde resin microcapsules of clomazone herbicide[J]. J Hebei Univ Sci Technol, 2010, 31(1): 48-51. (in Chinese)

徐春红, 张维东. 除草剂 2, 4-D丁酯药害产生的原因及预防措施[J]. 上海蔬菜, 2010(2): 73-74. XU Chunhong, ZHANG Weidong. The causes and preventive measures of phytotoxicity of the herbicide 2, 4-D-butyl ester[J]. Shanghai Veg, 2010(2): 73-74. (in Chinese)

ELBAHRI Z, TAVERDET J L. Optimization of an herbicide release from ethylcellulose microspheres[J]. Polym Bull, 2005, 54(4-5): 353-363.

华乃震. 农药剂型的进展和动向(中)[J]. 农药, 2008, 47(3): 157-160. HUA Naizhen. Advance and trend of pesticide formulation development[J]. Agrichemicals, 2008, 47(3): 157-160. (in Chinese)

王雅玲, 杨代斌, 袁会珠, 等. 低温胁迫下戊唑醇和苯醚甲环唑种子包衣对玉米种子出苗和幼苗的影响[J]. 农药学学报, 2009, 11(1): 59-64. WANG Yaling, YANG Daibin, YUAN Huizhu, et al. Effects of seed-coating tebuconazole and difenoconazole on emergence of maize seeds and response of seedling at chilling stress[J]. Chin J Pestic Sci, 2009, 11(1): 59-64. (in Chinese)

王娜. 戊唑醇微囊种衣剂的制备及其对玉米安全性机理[D]. 雅安: 四川农业大学, 2011: 16-35. WANG Na. The preparation of microcapsuled tebuconazole seed coatings formulation and its safety mechanism on maize [D]. Ya'an: Sichuan Agricultural University, 2011: 16-35. (in Chinese)

孙竹波, 孔繁华, 刘震, 等. 3.3% 1-甲基环丙烯微胶囊剂(聪明鲜)对柿子保鲜效果的影响[J]. 山东农业科学, 2007(4): 107-108. KONG Zhubo, KONG Fanhua, LIU Zhen, et al. Effect of 1-methylcyclopropene capsule on the freshness of persimmon[J]. Shandong Agric Sci, 2007(4): 107-108. (in Chinese)

ZHAO L J, YANG X N, LI X Y, et al. Antifungal, insecticidal and herbicidal properties of volatile components from paenibacillus polymyxa strain BMP-11[J]. Agric Sci China, 2011, 10(5): 728-736.

周一万, 冯俊涛, 张兴. 冬青油微囊悬浮剂的制备及其杀蚜活性研究[J]. 农药学学报, 2013, 15(2): 228-233. ZHOU Yiwan, FENG Juntao, ZHANG Xing. Preparation of wintergreen oil capsule suspension and control efficacy on Macrosiphoniella sanborni[J]. Chin J Pestic Sci, 2013, 15(2): 228-233. (in Chinese)

朱晓丽, 顾相伶, 张志国, 等. 单凝聚与复凝聚法制备昆虫激素十二醇微胶囊及其释放行为[J]. 高分子学报, 2007(5): 491-496. ZHU Xiaoli, GU Xiangling, ZHANG Zhiguo, et al. Preparation of insect sex pheromone dodecanol containing microcapsules by simple and complex coacervations and their release behavior[J]. Acta Polym Sin, 2007(5): 491-496. (in Chinese)

ATTERHOLT C A, DELWICHE M J, RICE R E, et al. Controlled release of insect sex pheromones from paraffin wax and emulsions[J]. J Controlled Release, 1999, 57(3): 233-247.

徐妍, 吴国林, 吴学民, 等. 梨小食心虫性信息素微囊化及释放特性[J]. 农药学学报, 2009, 11(1): 65-71. XU Yan, WU Guolin, WU Xuemin, et al. Microcapsulating and controlled release characteristics of sex pheromone of Grapholitha molesta[J]. Chin J Pestic Sci, 2009, 11(1): 65-71. (in Chinese)

KNIGHT A L, LIGHT D M. Adding microencapsulated pear ester to insecticides for control of Cydia pomonella (Lepidoptera: Tortricidae) in apple[J]. Pest Manag Sci, 2013, 69: 66-74.

曹坳程, 张文吉, 刘建华. 溴甲烷土壤消毒替代技术研究进展[J]. 植物保护, 2007, 33(1): 15-20. CAO Aocheng, ZHANG Wenji, LIU Jianhua. Progress in the alternatives to methyl bromide in soil disinfestation[J]. Plant Prot, 2007, 33(1): 15-20. (in Chinese)

曹坳程, 褚世海, 郭美霞, 等. 硫酰氟——溴甲烷土壤消毒潜在的替代品[J]. 农药学学报, 2002, 4(3): 91-93. CAO Aocheng, CHU Shihai, GUO Meixia, et al. Sulfuryl fluoride—a potential alternative to methyl bromide in soil fumigation[J]. Chin J Pestic Sci, 2002, 4(3): 91-93. (in Chinese)

张贵森. 不同壁材高效氯氰菊酯微囊悬浮剂应用及环境特性的影响 [D]. 泰安: 山东农业大学, 2012: 29-30. ZHANG Guisen. Effect of different wall material of Beta-cypermethrin microcapsule suspension on the differences of application environment characteristics [D]. Tai'an: Shandong Agricultural University, 2012: 29-30. (in Chinese)

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