α-苄基环十二酮肟酯的合成及其除草活性

刘建平; 李太公; 韩金涛; 王进敏; 王道全; 王明安

α-苄基环十二酮肟酯的合成及其除草活性

1.
中国农业大学应用化学系, 北京 100193

基金项目:

国家"十一五"科技支撑计划项目 (2006BAE01A01);教育部留学回国基金资助项目.

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出版历程
- 收稿日期: 2008-04-04

The Synthesis and Herbicidal Activity of α-Benzylcyclododecanone Oxime Esters

1.
Department of Applied Chemistry,China Agricultural University,Beijing 100193,China

摘要

摘要: 以环十二酮为原料,经过α-取代反应生成中间体α-苄基环十二酮,再与羟胺作用成肟,再经酯化反应合成了22个未见文献报道的α-苄基环十二酮肟酯衍生物,其化学结构经1H NMR、IR和元素分析确证。初步生物活性测定结果显示,部分化合物具有一定的除草活性,如 BWZ15 在浓度为100和1 mg/L时对马唐Digitaria sanguinalis的抑制率分别为72.70%和54.98%,对苘麻Abutilon theophrasti的抑制率分别为85.04%和81.91%。毒力测定结果显示, BWZ15 对马唐的IC50值和苘麻的IC90值分别为0.49和1.90 mg/L。
- α-苄基环十二酮 /
- α-苄基环十二酮肟酯 /
- 合成 /
- 除草活性
Abstract: Twenty-two novel compounds of α-benzylcyclododecanone oxime esters were synthesized by the acylation of α-benzylcyclododecanone oxime.Their structures were confirmed by 1H NMR,IR spectral data and elemental analysis.The preliminary bioassay results showed that BWZ15 had inhibition rate 72.70% and 54.98% against Digitaria sanguinalis and 85.04% and 81.91% against Abutilon theophrasti at the concentration of 100 and 1 mg/L,the IC50 value for D.sanguinalis and IC90 value for A.theophrasti of BWZ15 were 0.49 and 1.90 mg/L,respectively.
- α-benzylcyclododecanone /
- α-benzylcyclododecanone oxime ester /
- synthesis /
- herbicidal activity

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参考文献(17)

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