取代苯氧基三唑并嘧啶类化合物的合成及除草活性研究
Synthesis and Herbicidal Activity of Substitued Phenzoxy1,2,4-Triazolo Pyrimidine Derivatives
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摘要: 以砜基取代的嘧啶为关键中间体,设计合成了17个新型取代苯氧基1,2,4-三唑并 嘧啶类衍生物,通过元素分析、MS和1H NMR对所合成的化合物进行了结构表征。初步生物活性测定结果表明,100 mg/L浓度下部分化合物对6种测试靶标均表现出较好的抑制活性,盆栽复筛试验显示在150 g/hm2剂量下,5个化合物表现出较好的除草活性和持效性。
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关键词:
- 1,2,4-三唑并 嘧啶 /
- 合成 /
- 除草活性
Abstract: Seventeen novel substitued phenzoxy 1,2,4-triazolo pyrimidine derivatives have been designed and synthesized using sulfone substituted 1,2,4-triazolo pyrimidine as starting material.All synthesized compounds were confirmed by elemental analysis,MS and 1H NMR.Preliminary bioassay indicates that some of them display good herbicidal activities at concentration of 100 mg/L.Five compounds exhibited good herbicidal activities and continuousness under dosage of 150 g/hm2.-
Key words:
- 1,2,4-triazolo pyrimidine /
- synthesis /
- herbicidal activity
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