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苦皮藤素V在粘虫和小地老虎幼虫体内的穿透与代谢

刘伟 姬志勤 吴文君 魏少鹏

刘伟, 姬志勤, 吴文君, 魏少鹏. 苦皮藤素V在粘虫和小地老虎幼虫体内的穿透与代谢[J]. 农药学学报, 2015, 17(3): 285-290. doi: 10.3969/j.issn.1008-7303.2015.03.06
引用本文: 刘伟, 姬志勤, 吴文君, 魏少鹏. 苦皮藤素V在粘虫和小地老虎幼虫体内的穿透与代谢[J]. 农药学学报, 2015, 17(3): 285-290. doi: 10.3969/j.issn.1008-7303.2015.03.06
Liu Wei, Ji Zhiqin, Wu Wenjun, Wei Shaopeng. Investigation on the penetration and metabolism of celangulin V in the larvae of Mythimna separata and Agrotis ypsilon[J]. Chinese Journal of Pesticide Science, 2015, 17(3): 285-290. doi: 10.3969/j.issn.1008-7303.2015.03.06
Citation: Liu Wei, Ji Zhiqin, Wu Wenjun, Wei Shaopeng. Investigation on the penetration and metabolism of celangulin V in the larvae of Mythimna separata and Agrotis ypsilon[J]. Chinese Journal of Pesticide Science, 2015, 17(3): 285-290. doi: 10.3969/j.issn.1008-7303.2015.03.06

苦皮藤素V在粘虫和小地老虎幼虫体内的穿透与代谢

doi: 10.3969/j.issn.1008-7303.2015.03.06
基金项目: 

国家自然科学基金资助项目(31371973,31301700);陕西省自然科学基金资助项目(2013JQ3003);中央高校基本科研业务费专项(QN2013009).

Investigation on the penetration and metabolism of celangulin V in the larvae of Mythimna separata and Agrotis ypsilon

  • 摘要: 采用高效液相色谱技术研究了苦皮藤素Ⅴ在粘虫Mythimna separata和小地老虎Agrotis ypsilon幼虫中的穿透及代谢。结果表明:苦皮藤素V均不能从粘虫和小地老虎幼虫的体壁穿透到血腔或从血腔穿透到中肠,但很容易从中肠穿透到血腔,且穿透速率无差异;苦皮藤素V在小地老虎幼虫体内的代谢解毒速率远大于其在粘虫幼虫体内的代谢速率,其半衰期分别为5.5和13.1 h。本研究结果表明,苦皮藤素V对粘虫和小地老虎幼虫的选择毒杀作用与药物的穿透能力无关,其在试虫体内的解毒代谢差异才是其对昆虫具有选择作用的机理之一。
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出版历程
  • 收稿日期:  2014-11-10
  • 修回日期:  2015-03-03
  • 刊出日期:  2015-06-11

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